METHOD FOR ASSESSING EFFICIENCY OF TREATMENT OF CHRONIC GENERALIZED PARODONTITIS IN PREGNANT WOMEN

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine, namely to dentistry, and can be used to assess the effectiveness of treatment of chronic generalized periodontitis (CGP) in pregnant women. Oral and gingival fluid of a woman in the second trimester of pregnancy is studied prior to treatment, then 30 days after the start of treatment. Content of osteoprotegerin OPG, pg/ml, is determined in the oral fluid prior to treatment – OPG₀, 30 days after the start of treatment – OPG₃₀. Concentration of Katelecidin LL37 (K), pg/ml, is determined in the gingival fluid before treatment – K₀, 30 days after the start of treatment – K₃₀. Indicators P₁ and P₂ are calculated by formulas: P₁ = OPG₃₀ – OPG₀, P₂ = K₀ – K₃₀. If conditions P₁≥3.2 and P₂≥1.6 are simultaneously fulfilled, treatment is assessed as effective.;EFFECT: proposed method provides a high degree of reliability of assessment of effectiveness of treatment of mild and moderate CGP in pregnant women.;1 cl