ANTI-TUBERCULOSIS STABLE PHARMACEUTICAL COMPOSITION IN A FORM OF A COATED TABLET COMPRISING GRANULES OF ISONIAZID AND GRANULES OF RIFAPENTINE AND ITS PROCESS OF PREPARATION

摘要

FIELD: medicine.;SUBSTANCE: present invention relates to medicine, in particular to an oral pharmaceutical fixed dose composition and its process of preparation for use in the treatment of tuberculosis, wherein said oral pharmaceutical composition comprises: granules comprising isoniazid; granules comprising rifapentine; and at least one extragranular excipient.;EFFECT: implementation of the invention allows producing a chemically stable pharmaceutical fixed dose composition, comprising rifapentine and isoniazid.;11 cl, 2 tbl, 1 ex