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METHOD FOR DETERMINING PREDICTION OF COMPLICATIONS OF CARDIOVASCULAR DISEASES DURING EXTREME CHANGES IN CLIMATIC CONDITIONS

机译:确定气候条件极端变化期间心血管疾病并发症的预测方法

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, namely to cardiology and preventive medicine, and discloses a method for determining predisposition to development of complications of cardiovascular diseases in extreme climatic changes. Method is characterized by that blood is collected in patients, level of free-radical oxidation of malonic dialdehyde (MDA) in blood plasma is determined, activity of antioxidant enzyme superoxide dismutase (SOD) in erythrocytes is determined, MDA / SOD ratio is calculated and if the value of this ratio is increased by more than 20 % compared to the initial value during extreme weather conditions, the risk of cardiovascular complications is considered to be high. Method provides higher prediction accuracy and reduced risk of cardiovascular complications.;EFFECT: invention can be used to prevent a risk of developing complications of cardiovascular diseases in the period of "heat waves".;1 cl, 3 tbl, 3 ex
机译:技术领域本发明涉及医学,即心脏病学和预防医学,并且公开了一种在极端气候变化中确定心血管疾病并发症发展的易感性的方法。该方法的特点是收集患者的血液,测定血浆中丙二醛(MDA)的自由基氧化水平,测定红细胞中抗氧化酶超氧化物歧化酶(SOD)的活性,计算MDA / SOD比,如果此值的值与极端天气条件下的初始值相比增加了20%以上,则心血管并发症的风险被认为很高。该方法提供了更高的预测准确度并降低了心血管并发症的风险。;效果:本发明可用于防止在“热浪”时期发生心血管疾病并发症的风险。; 1 cl,3 tbl,3 ex

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