首页> 外国专利> METHOD FOR ASSESSING DAMAGING EFFECT OF CYTOMEGALOVIRAL INFECTION ON MYRISTIC ACID CONTENT IN UMBILICAL CORD BLOOD OF NEWBORNS FROM MOTHERS SUFFERED CYTOMEGALOVIRUS INFECTION REACTIVATION IN THIRD TRIMESTER

METHOD FOR ASSESSING DAMAGING EFFECT OF CYTOMEGALOVIRAL INFECTION ON MYRISTIC ACID CONTENT IN UMBILICAL CORD BLOOD OF NEWBORNS FROM MOTHERS SUFFERED CYTOMEGALOVIRUS INFECTION REACTIVATION IN THIRD TRIMESTER

机译:评估母亲经第三轮三角帆病毒感染激活后新生儿脐带血中球藻病毒感染对肉豆蔻酸含量的破坏作用评估方法

摘要

FIELD: medicine.;SUBSTANCE: invention relates to obstetrics, as well as to scientific research - pathological physiology. Substance of the invention consists in the fact that in the blood of the umbilical cord of newborns the titre of the class G antibodies to the cytomegalovirus is determined, the content of myristic acid is determined in the erythrocyte membrane by a gas chromatography method, and the microviscosity of the lipid bilayer in the erythrocyte membrane is determined by the lateral diffusion of the fluorescent hydrophobic probene probe. If class G antibody titre is increased to 1:1600 cytomegalovirus, umbilical cord erythrocytes increase in myristic acid content to 1.64 ± 0.007 %, increased microviscosity of the lipid bilayer with reduced pyrene excimerisation coefficient to 0.48 ± 0.004 Fe/Fm, assessing the risk of developing hypoxia of the newborn child.;EFFECT: invention is intended for assessing the risk of developing hypoxia of newborns during reactivation of cytomegalovirus infection in the mother in the third trimester.;1 cl
机译:技术领域本发明涉及产科以及科学研究-病理生理学。本发明的实质在于,在新生儿的脐带血中测定针对巨细胞病毒的G类抗体的滴度,通过气相色谱法测定红细胞膜中肉豆蔻酸的含量,并且红细胞膜中脂双层的微粘度由荧光疏水hydrophobic探针的横向扩散确定。如果将G类抗体滴度提高至1:1600巨细胞病毒,则脐带红细胞的肉豆蔻酸含量增加至1.64±0.007%,脂质双层的微粘度增加,pyr激发性系数降低至0.48±0.004 Fe / Fm,从而评估了效果:本发明旨在评估在妊娠晚期母亲巨细胞病毒感染重新激活期间新生儿发生缺氧的风险。1cl

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号