首页> 外国专利> METHOD FOR PREDICTING SEVERITY OF ATOPIC DERMATITIS IN CHILDREN WITH ACCOMPANYING INTESTINAL DYSBACTERIOSIS

METHOD FOR PREDICTING SEVERITY OF ATOPIC DERMATITIS IN CHILDREN WITH ACCOMPANYING INTESTINAL DYSBACTERIOSIS

机译:预测伴有肠梗阻的儿童原子性皮肤炎严重程度的方法

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, namely to dermatology, and represents a method for prediction of severity of atopic dermatitis in children with intestinal dysbacteriosis, consisting in the fact that before the treatment, the feces are microbiologically analyzed with the species identification of all the recovered cultures of the microorganisms by MALDI-TOF mass spectrometry and if the initial content of Bifidobacterium longum is 107 CFU/g and lower, Lactobacillus acidophilus – 105 CFU/g and lower, Escherichia coli – 106 CFU/g and lower, Enterococcus faecalis or Enterococcus faecium – 107 CFU/g and higher, haemolytic strains of Escherichia coli or any other types of enterobacteria, except for typical Escherichia coli, – 105 CFU/g and higher, any other types of opportunistic microorganisms in concentrations of 104 CFU/g and higher is predicted a risk of aggravated intestinal dysbacteriosis worsening the course of atopic dermatitis in children, and transition of disease into more severe clinical version with traditional therapy.;EFFECT: invention provides early diagnosis and prediction of transition of atopic dermatitis in children to a more severe clinical version.;1 cl, 3 ex, 3 tbl
机译:技术领域本发明涉及医学,即皮肤病学,并且代表一种用于预测肠道菌群失调患儿特应性皮炎严重程度的方法,其特征在于,在治疗之前,对粪便进行微生物学分析。 MALDI-TOF质谱法鉴定所有回收的微生物培养物,如果长双歧杆菌的初始含量为10 7 CFU / g和更低,则嗜酸乳杆菌– 10 5 CFU / g及以下,大肠杆菌– 10 6 CFU / g及以下,粪肠球菌或粪肠球菌– 10 7 CFU / g及以上,大肠埃希菌的溶血菌株大肠杆菌或任何其他类型的肠细菌,除了典型的大肠杆菌– 10 5 CFU / g和更高,任何其他类型的机会微生物的浓度为10 4 CFU / g或更高可预测加重肠道菌群失调的风险儿童特应性皮炎的病程,以及通过传统疗法将疾病转变为更严重的临床版本。效果:本发明提供了儿童特应性皮炎向更严重的临床版本转变的早期诊断和预测。1cl,3例如,3汤匙

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