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METHOD FOR DETECTING A PANCREATIC TUMOR, AN ANTIBODY AND A KIT FOR DETECTING A PANCREATIC TUMOR

机译:检测胰腺肿瘤的方法,抗体和检测胰腺肿瘤的工具包

摘要

FIELD: medicine.;SUBSTANCE: group of inventions relates to medicine and concerns method for detecting pancreatic cancer or a benign pancreatic tumor by measuring the number of versions of the APOA2 protein in a body fluid sample of the analysed individual, which comprises (A) a first step of measuring, in a sample, the amount of APOA2-ATQ protein using an antibody against end of APOA2-ATQ and antibody not against end of APOA2-ATQ; (B) a second step of measuring, in a sample, the amount of APOA2-AT protein using the anti-APOA2-AT end antibody and the non anti-APOA2-AT end antibody; and (C) a third step of inputting into a predetermined logistic regression expression a measured protein APOA2-ATQ and a measured protein APOA2-AT and determining a pancreatic cancer or benign pancreatic tumor in an individual being examined, if the resultant discriminator value of the analysed individual statistically significantly differs from the discriminant value of the normal individual. Group of inventions also relates kit for detecting pancreatic cancer or a benign pancreatic tumor containing two or more types of said antibodies.;EFFECT: group of inventions provides detection of pancreatic cancer or benign pancreatic tumor.;11 cl, 12 dwg, 5 tbl, 11 ex
机译:领域:发明领域本发明涉及医学,并且涉及通过测量被分析个体的体液样品中APOA2蛋白版本的数量来检测胰腺癌或良性胰腺肿瘤的方法,包括(A)第一步,使用抗APOA2-ATQ末端的抗体和不抗APOA2-ATQ末端的抗体测量样品中APOA2-ATQ蛋白的量; (B)使用抗APOA2-AT末端抗体和非抗APOA2-AT末端抗体测量样品中APOA2-AT蛋白质的量的第二步; (C)第三步,将测定的蛋白APOA2-ATQ和测定的蛋白APOA2-AT输入到预定的逻辑回归表达式中,并确定被检个体的胰腺癌或良性胰腺肿瘤,如果得到的鉴别值被分析的个体在统计学上与正常个体的判别值显着不同。一组发明还涉及用于检测胰腺癌或良性胰腺肿瘤的试剂盒,其含有两种或多种所述抗体。效果:一组发明提供了对胰腺癌或良性胰腺肿瘤的检测。 11前

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