首页> 外国专利> IMMUNOTHERAPY BY USING CELL CAPABLE OF CO-EXPRESSING TARGET ANTIGEN AND CD1d AND PULSED WITH CD1d LIGAND

IMMUNOTHERAPY BY USING CELL CAPABLE OF CO-EXPRESSING TARGET ANTIGEN AND CD1d AND PULSED WITH CD1d LIGAND

机译:通过使用具有共表达靶抗原和CD1d能力的细胞进行免疫治疗并与CD1d配体脉冲

摘要

The present invention provides a novel immunity induction method, particularly, a method of simultaneously inducing activation of NKT cells and T-cell immune responses. To be more precise, the present invention provides a target antigen and CD1d co-expressing cell, and a preparation and identification method thereof; a target antigen and CD1d co-expressing cell capable of activating immunity to the target antigen, and a preparation method thereof; an immunoinducer to a target antigen or a pharmaceutical agent, which contains a target antigen and CD1d co-expressing cell capable of activating immunity to the target antigen; a target antigen and CD1d co-expressing vector; a kit containing an expression vector and/or a CD1d ligand; and the like.
机译:本发明提供了一种新颖的免疫诱导方法,特别是同时诱导NKT细胞激活和T细胞免疫应答的方法。更准确地说,本发明提供了靶抗原和CD1d共表达细胞,及其制备和鉴定方法。能够激活针对靶抗原的免疫力的靶抗原和CD1d共表达细胞及其制备方法;靶抗原或药物的免疫诱导剂,其包含靶抗原和能够激活对靶抗原的免疫力的CD1d共表达细胞;靶抗原和CD1d共表达载体;包含表达载体和/或CD1d配体的试剂盒;等等。

著录项

  • 公开/公告号EP1990410B1

    专利类型

  • 公开/公告日2020-01-08

    原文格式PDF

  • 申请/专利权人 RIKEN;

    申请/专利号EP20070714709

  • 发明设计人 FUJII SHIN-ICHIRO;SHIMIZU KANAKO;

    申请日2007-02-21

  • 分类号C12N15;A61K35/12;A61K35/14;A61P31;A61P31/12;A61P35;A61P37/04;C12N5/10;C12N15/09;C12Q1/02;A61K39;A61K39/02;A61K39/12;

  • 国家 EP

  • 入库时间 2022-08-21 11:42:54

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