首页> 外国专利> METHOD FOR PRODUCING MYOCARDIAL STEM CELL USED FOR TREATMENT AND/OR PREVENTION OF CARDIAC ARREST

METHOD FOR PRODUCING MYOCARDIAL STEM CELL USED FOR TREATMENT AND/OR PREVENTION OF CARDIAC ARREST

机译:制备用于治疗和/或预防心脏骤停的心肌干细胞的方法

摘要

[Problem to be Solved]An object of the present invention is to provide a novel myocardial stem cell for transplantation which enables maintenance of a therapeutic effect on and/or preventive effect against cardiac failure for a prolonged period, a method for producing the myocardial stem cell, and a cell preparation containing the myocardial stem cell.[Solution]The present invention relates to a method for producing a myocardial stem cell to be used for treatment and/or prevention of cardiac failure, the method comprising the step of introducing a complex of a mitochondria-targeting carrier and a mitochondria activating agent into a myocardial stem cell; a cell produced by the method and a cell preparation containing the cell; and a liposome to be used for producing the cell. According to the present invention, there can be provided a myocardial stem cell which is capable of maintaining a therapeutic effect and/or preventive effect by cell transplantation for a prolonged period.
机译:[解决的问题]本发明的目的是提供一种新型的用于移植的心肌干细胞,其能够长期维持对心力衰竭的治疗作用和/或对心力衰竭的预防作用,一种生产心肌梗的方法细胞和含有心肌干细胞的细胞制剂。溶液技术领域本发明涉及一种用于治疗和/或预防心力衰竭的心肌干细胞的生产方法,该方法包括引入复合物的步骤。将靶向线粒体的载体和线粒体活化剂引入心肌干细胞中;通过该方法生产的细胞和含有该细胞的细胞制剂;以及用于产生细胞的脂质体。根据本发明,可以提供能够通过细胞移植长期维持治疗效果和/或预防效果的心肌干细胞。

著录项

  • 公开/公告号EP3542822A4

    专利类型

  • 公开/公告日2020-08-19

    原文格式PDF

  • 申请/专利权人 LUCA SCIENCE INC.;

    申请/专利号EP20170871400

  • 申请日2017-11-16

  • 分类号A61K45;A61K9;A61K9/127;A61K31/05;A61K35/34;A61K47/24;A61K47/42;A61P9/04;C12N5/074;

  • 国家 EP

  • 入库时间 2022-08-21 11:41:58

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