首页> 外国专利> METHOD FOR PRODUCING MYOCARDIAL STEM CELL USED FOR TREATMENT AND/OR PREVENTION OF CARDIAC ARREST

METHOD FOR PRODUCING MYOCARDIAL STEM CELL USED FOR TREATMENT AND/OR PREVENTION OF CARDIAC ARREST

机译:制备用于治疗和/或预防心脏骤停的心肌干细胞的方法

摘要

An object of the present invention is to provide a novel myocardial stem cell for transplantation which enables maintenance of a therapeutic effect on and/or preventive effect against cardiac failure for a prolonged period, a method for producing the myocardial stem cell, and a cell preparation containing the myocardial stem cell.;[Solution];The present invention relates to a method for producing a myocardial stem cell to be used for treatment and/or prevention of cardiac failure, the method comprising the step of introducing a complex of a mitochondria-targeting carrier and a mitochondria activating agent into a myocardial stem cell; a cell produced by the method and a cell preparation containing the cell; and a liposome to be used for producing the cell. According to the present invention, there can be provided a myocardial stem cell which is capable of maintaining a therapeutic effect and/or preventive effect by cell transplantation for a prolonged period.
机译:本发明的目的是提供一种新型的用于移植的心肌干细胞,其能够长期维持对心力衰竭的治疗作用和/或预防作用,制备心肌干细胞的方法和细胞制剂。解决方案;本发明涉及一种生产用于治疗和/或预防心力衰竭的心肌干细胞的方法,该方法包括引入线粒体-复合物的步骤。将载体和线粒体活化剂靶向心肌干细胞;通过该方法生产的细胞和含有该细胞的细胞制剂;以及用于产生细胞的脂质体。根据本发明,可以提供能够通过细胞移植长期维持治疗效果和/或预防效果的心肌干细胞。

著录项

  • 公开/公告号US2020032214A1

    专利类型

  • 公开/公告日2020-01-30

    原文格式PDF

  • 申请/专利权人 LUCA SCIENCE INC.;

    申请/专利号US201716349788

  • 申请日2017-11-16

  • 分类号C12N5/0775;A61K35/34;A61K31/05;A61K9/127;A61P9/04;

  • 国家 US

  • 入库时间 2022-08-21 11:20:37

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