首页> 外国专利> PROCESS FOR THE PREPARATION OF 2-(3,6-DIHALOPYRIDIN-2-YL)-3H-IMIDAZOL4,5-CPYRIDINE DERIVATIVES AND RELATED COMPOUNDS BY REACTING THE 3H-IMIDAZOL4,5-CPYRIDINE DERIVATIVE WITH A METAL-ORGANIC ZINC-AMINE BASE

PROCESS FOR THE PREPARATION OF 2-(3,6-DIHALOPYRIDIN-2-YL)-3H-IMIDAZOL4,5-CPYRIDINE DERIVATIVES AND RELATED COMPOUNDS BY REACTING THE 3H-IMIDAZOL4,5-CPYRIDINE DERIVATIVE WITH A METAL-ORGANIC ZINC-AMINE BASE

机译:通过使3H-咪唑[4,5-C]吡啶衍生物与3H-咪唑[4,5-C]吡啶衍生物反应制取2-(3,6-二氢吡啶-2-基)-3H-咪唑[4,5-C]吡啶衍生物及相关化合物的方法金属有机锌碱

摘要

The invention relates to a method for producing halogenated pyridine derivatives of formula (II) from compounds of the Q-H structure via intermediate steps of formula (IIIa) or (IIIb) in which Q is a structural element, where the character # indicates the binding to the radical of the molecule and A, Q1, Q2, Q3, Q4, Q5 and Q6 have the designations provided in the description, W is halogen, and Y is halogen, CO2R1 or NO2, where R1 is (C1-C6) alkyl or (C1-C6) haloalkyl, and R2 is halogen or -O-pivaloyl.
机译:本发明涉及通过式(IIIa)或(IIIb)的中间步骤由QH结构的化合物制备式(II)的卤代吡啶衍生物的方法,其中Q是结构元素,其中字符#表示与分子的原子团以及A,Q1,Q2,Q3,Q4,Q5和Q6具有描述中提供的名称,W是卤素,Y是卤素,CO2R1或NO2,其中R1是(C1-C6)烷基或(C1-C6)卤代烷基,且R2为卤素或-O-新戊酰基。

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