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PROCESS FOR THE PREPARATION OF WATER-IN-OIL AND OIL-IN-WATER NANOEMULSIONS

机译:油包水型和水包油型纳米乳液的制备方法

摘要

Process for the preparation of a water-in-oil or oil-in-water nanoemulsion wherein the dispersed phase is distributed in the dispersing phase in the form of droplets having a diameter ranging from 1 to 500 nm, comprising: 1) the preparation of a homogeneous water/oil blend (I) characterized by an interface tension lower than 1 mN/m, comprising water in an amount of 30 to 70% by weight, at least two surface-active agents having a different HLB, selected from non-ionic, anionic, polymeric surface-active agents, said surface-active agents being present in such a quantity as to make the blend homogeneous; 2) the dilution of the blend (I) in a dispersing phase consisting of oil or water with the addition of a surface-active agent, selected from non-ionic, anionic, polymeric surface-active agents, the quantity of the dispersing phase and surface-active agent being such as to obtain a nanoemulsion having a HLB different from that of the blend (I).
机译:制备油包水或水包油纳米乳液的方法,其中分散相以直径为1至500 nm的液滴形式分散在分散相中,包括:1)制备一种均匀的水/油共混物(I),其界面张力低于1 mN / m,包含30%至70%重量的水,至少两种具有不同HLB的表面活性剂,选自非离子,阴离子,聚合物表面活性剂,所述表面活性剂的存在量应使混合物均匀。 2)在由油或水组成的分散相中稀释共混物(I),并添加表面活性剂(选自非离子,阴离子,聚合物表面活性剂),分散相的量和表面活性剂是用于获得具有不同于共混物(I)的HLB的纳米乳液。

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