DETECTION REAGENT AND KIT FOR IDENTIFYING ACIDIC STATE AND GLYCATION STATE OF LOW DENSITY LIPOPROTEIN

摘要

The present invention provides a detection reagent for comprehensively detecting an oxidized state and a glycated state of a low-density lipoprotein. More specifically, according to the present invention, while an oxidized low-density lipoprotein and a glycated low-density lipoprotein are detected with a fluolophore-labelled antibody, a lipid radical is detected with a fluorescent nitroxide 2,2,6-trimethyl-4-(4-nitrobenzo[1,2,5]oxadiazol-7-ylamino)-6-pentylpiperadine-1-ox yl (NBD-Pen).