首页> 外国专利> TREATMENT OF LEUKEMIA WITH HISTONE DEACETYLASE INHIBITORS

TREATMENT OF LEUKEMIA WITH HISTONE DEACETYLASE INHIBITORS

机译:组蛋白去乙酰化酶抑制剂治疗白血病

摘要

Provided herein are combinations comprising an HDAC inhibitor and azacitidine for the treatment of leukemia in a subject in need thereof. Provided herein are combinations comprising an HDAC inhibitor and azacitidine for the treatment of acute myelogenous leukemia in a subject in need thereof. Also provided herein are methods for treating leukemia in a subject in need thereof, comprising administering to the subject an effective amount of the above combination or an HDAC inhibitor, as well as methods for treating acute myelogenous leukemia in a subject in need thereof, comprising administering to the subject an effective amount of the above combination or an HDAC inhibitor.
机译:本文提供了包含HDAC抑制剂和阿扎胞苷的组合,用于在有需要的受试者中治疗白血病。本文提供了包含HDAC抑制剂和阿扎胞苷的组合,用于在有此需要的受试者中治疗急性骨髓性白血病。本文还提供了在有此需要的受试者中治疗白血病的方法,包括向该受试者施用有效量的上述组合或HDAC抑制剂,以及在有此需要的受试者中治疗急性骨髓性白血病的方法,包括给药对受试者有效量的上述组合或HDAC抑制剂。

著录项

  • 公开/公告号EP3166603B1

    专利类型

  • 公开/公告日2020-02-12

    原文格式PDF

  • 申请/专利权人 ACETYLON PHARMACEUTICALS INC.;TAMANG DAVID LEE;

    申请/专利号EP20150818585

  • 发明设计人 JONES SIMON S.;MIN CHENGYIN;YANG MIN;

    申请日2015-07-06

  • 分类号A61K31/4184;A61K31/706;A61P35/02;A61K45/06;A61K31/167;A61K31/4045;A61K31/496;A61K31/505;A61K31/506;A61K31/5377;A61P35;

  • 国家 EP

  • 入库时间 2022-08-21 11:41:21

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