11C-LABELLED CATECHOL DERIVATIVE, POSITRON EMISSION TOMOGRAPHY (PET) PROBE FOR PHOSPHORYLATED TAU AGGREGATION INHIBITOR USING SAME, AND PRODUCTION METHODS THEREFOR

摘要

An object of the invention is to provide an 11 C-labeled catechol derivative having sufficient radioactivity to obtain an imaging image by a PET apparatus, a PET probe of a phosphorylated tau aggregation inhibitor using the same, and a method for producing them. The 11 C -labeled catechol derivative of the present invention is represented by the following general formula (a) (wherein R is a substituent having an isopropylamino group, and the carbon at the 2-position of the isopropylamino group is labeled with 11 C).