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MELANIN PRODUCTION INHIBITOR, SKIN-LIGHTENING AGENT, FIBROBLAST CELL ACTIVATOR, COLLAGEN AND/OR ELASTIN PRODUCTION PROMOTOR, AND WRINKLE-IMPROVING AGENT
MELANIN PRODUCTION INHIBITOR, SKIN-LIGHTENING AGENT, FIBROBLAST CELL ACTIVATOR, COLLAGEN AND/OR ELASTIN PRODUCTION PROMOTOR, AND WRINKLE-IMPROVING AGENT
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机译:黑色素生产抑制剂,美白皮肤剂,成纤维细胞活化剂,胶原蛋白和/或弹性蛋白生产促进剂以及除皱剂
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摘要
The present invention provides an agent containing an orotic acid derivative that has high solubility in solvent and has superior physiological activity. The agent of the present invention is a melanin production inhibitor, whitening agent, fibroblast activator, collagen and/or elastin production promoter or wrinkle ameliorant containing as an active ingredient thereof an orotic acid derivative represented by the following general formula (1) or a salt thereof. In formula (1), R preferably represents a side chain of glutamic acid, glycine, histidine or aspartic acid. [In formula (1), R represents a side chain of a naturally-occurring amino acid and R may form, together with a nitrogen atom adjacent thereto through a single carbon atom, a hetero ring.]
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