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NITROGEN-CONTAINING CONDENSED RING COMPOUND HAVING DOPAMINE D3 RECEPTOR ANTAGONISTIC EFFECT

机译:具有多巴胺D3受体拮抗作用的含氮稠环化合物

摘要

Novel compounds having D3 receptor antagonistic activity are provided. A compound represented by formula (I):whereinring A is a heterocycle, Xis each independently CRR, Xis each independently CRR, Yand Yare each independently a carbon atom or a nitrogen atom,L is -N(R)-C(=O)- or the like, W is cyclyl or the like, Rand Rare each independently substituted or unsubstituted alkyl or the like, R, R, Rto R, and Rare each independently hydrogen atoms or the like,p is 1 or 2, q is an integer of 1 to 3, n is an integer of 1 to 4, s is an integer of 0 to 4, or a pharmaceutically acceptable salt thereof.
机译:提供了具有D3受体拮抗活性的新型化合物。由式(I)表示的化合物:其中A是杂环,Xis各自独立地为CRR,Xis各自独立地为CRR,Yand Yare各自独立地为碳原子或氮原子,L为-N(R)-C(= O) -等,W是环基等,Rand Rare各自独立地为取代或未取代的烷基等,R,R,Rto R和Rare各自独立地为氢原子等,p为1或2,q为1至3的整数,n为1至4的整数,s为0至4的整数或其药学上可接受的盐。

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