METHODS FOR SELECTIVE EXPANSION OF DELTA 3 GAMMA DELTA T-CELL POPULATIONS AND COMPOSITIONS THEREOF

摘要

The present application is directed to agents that bind an epitope specific to a δ3 γδ TCR. Such agents can be, but are not limited to, an antibody or fragment thereof. Also described herein are methods for using the agents, e.g., to expand or selectively expand δ3 γδ T cells. Also described herein are methods of using expanded δ3 γδ T cells for treatment of a subject in need thereof.