METHODS FOR SELECTIVE EXPANSION OF .DELTA.3 .GAMMA..DELTA. T-CELL POPULATIONS AND COMPOSITIONS THEREOF

摘要

The present application is directed to agents that bind an epitope specific to a d3 ?d TCR. Such agents can be, but are not limited to, an antibody or fragment thereof. Also described herein are methods for using the agents, e.g., to expand or selectively expand d3 ?d T cells. Also described herein are methods of using expanded d3 ?d T cells for treatment of a subject in need thereof.