SELECTIVE ENRICHMENT OF A POPULATION OF DNA IN A MIXED DNA SAMPLE THROUGH TARGETED SUPPRESSION OF DNA AMPLIFICATION

摘要

The present disclosure provides method and products for the selective enrichment of one population of DNA in a mixed sample comprising multiple populations of DNA. In some embodiments, the mixed sample comprises one or more populations of microbial DNA and the mammalian host DNA, particularly including pathogenic microbial DNA mixed with mammalian host DNA in a clinical sample from an infected individual.