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NOVEL POLY(ETHYLENE GLYCOL) DERIVATIVE AND PROTEIN-ADSORPTION INHIBITOR
NOVEL POLY(ETHYLENE GLYCOL) DERIVATIVE AND PROTEIN-ADSORPTION INHIBITOR
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机译:新型聚乙烯(乙二醇)衍生物和蛋白质吸附抑制剂
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摘要
A compound is provided which is effectively adsorbed to a substrate surface, such as an immune reaction vessel, has extremely high protein adsorption inhibitory effect that inhibits non-specific adsorption of protein or the like, and has excellent washability to retain the inhibitory effect before and after washing operation of the substrate. Also provided are a protein adsorption inhibitor using the compound, a phosphorylcholine-modified substrate, and a method for inhibiting protein adsorption. The compound is a phosphorylcholine group-containing polyethylene glycol derivative represented by formula (1). The method for inhibiting protein adsorption of the present invention includes the step of forming an adsorbed layer of the derivative on a substrate surface.展开▼
机译:提供了一种化合物,该化合物可有效吸附至免疫反应容器等基质表面,具有极高的蛋白质吸附抑制作用,可抑制蛋白质等的非特异性吸附,并且具有优异的可洗性,以保持之前和之后的抑制作用。在基板的清洗操作之后。还提供了使用该化合物的蛋白质吸附抑制剂,磷酸胆碱改性的底物以及抑制蛋白质吸附的方法。该化合物是由式(1)表示的含磷胆碱基团的聚乙二醇衍生物。本发明的抑制蛋白质吸附的方法包括在基材表面上形成衍生物的吸附层的步骤。 <图像文件=“ IMGA0001.GIF” he =“ 16” imgContent =“ chem” imgFormat =“ GIF” wi =“ 145” /> Chemistry>
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