首页> 外国专利> BACILLUS SUBTILIS STRAINS IMPROVING ANIMAL PERFORMANCE PARAMETERS

BACILLUS SUBTILIS STRAINS IMPROVING ANIMAL PERFORMANCE PARAMETERS

机译:芽孢杆菌菌株改善动物性能参数

摘要

The present invention provides a Bacillus subtilis strain selected from the group consisting of a) the strain deposited as DSM32324, b) the strain deposited as DSM32325, and c) a mutant strain of (a) or (b) which has sensitivity for ampicillin, vancomycin, gentamicin, kanamycin, streptomycin, erythromycin, clindamycin, tetracycline, and chloramphenicol; and has inhibitory activity against E. coli and Clostridium perfringens. The invention further relates to Bacillus compositions comprising at least one Bacillus subtilis strain of the invention, preferably the Bacillus subtilis strain DSM32324 and/or the Bacillus subtilis strain DSM32325, as Direct Fed Microbial (DFM), premix, animal feed additive or animal feed. The invention provides a method of improving one or more animal performance parameters selected from the group consisting of i) increased weight gain (WG), ii) lower feed conversion ratio (FCR), iii) lower necrotic enteritis lesion scoring, iv) lower necrotic enteritis frequency, v) lower necrotic enteritis mortality, vi) increased European Production Efficacy Factor (EPEF), and vii) lower mortality, by feeding a strain or a composition according to the invention to an animal.
机译:本发明提供了一种枯草芽孢杆菌菌株,其选自:a)以DSM32324保藏的菌株,b)以DSM32325保藏的菌株,以及c)对氨苄青霉素敏感的(a)或(b)突变菌株,万古霉素,庆大霉素,卡那霉素,链霉素,红霉素,克林霉素,四环素和氯霉素;对大肠杆菌和产气荚膜梭菌具有抑制活性。本发明进一步涉及芽孢杆菌组合物,其包含至少一种本发明的枯草芽孢杆菌菌株,优选枯草芽孢杆菌菌株DSM32324和/或枯草芽孢杆菌菌株DSM32325,作为直接饲喂微生物(DFM),预混料,动物饲料添加剂或动物饲料。本发明提供了一种改善一个或多个选自以下的动物性能参数的方法:i)增加的体重增加(WG),ii)较低的饲料转化率(FCR),iii)较低的坏死性肠炎病变评分,iv)较低的坏死性肠炎发生率,v)降低坏死性肠炎死亡率,vi)通过将根据本发明的菌株或组合物饲喂给动物来提高欧洲生产效率因子(EPEF),以及vii)降低死亡率。

著录项

  • 公开/公告号EP3596238A1

    专利类型

  • 公开/公告日2020-01-22

    原文格式PDF

  • 申请/专利权人 CHR. HANSEN A/S;

    申请/专利号EP20180714452

  • 发明设计人 SANDVANG DORTHE;STYRISHAVE TINA;

    申请日2018-03-14

  • 分类号C12R1/125;A61K35/742;C12N1/20;A23K10/16;A23K10/18;

  • 国家 EP

  • 入库时间 2022-08-21 11:39:06

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