COMPOSITIONS AND METHODS FOR TREATING SEPTIC CARDIOMYOPATHY

摘要

Methods and compositions are provided for treating sepsis-associated cardiac dysfunction, specifically sepsis-induced cardiomyopathy, and for protecting the heart from sepsis-associated dysfunction and improving cardiac function in subjects having sepsis. These methods include administering compositions comprising secoisolariciresinol diglucoside (SDG) or related compounds, obtained from natural sources, such as flaxseed, or generated synthetically.