EVALUATION SYSTEM OF ANTICANCER AGENT FOCUSING ON HP1 FUNCTION

摘要

To provide a method for evaluation of chromosome instability of a cancer cell, and a system therefor.SOLUTION: Evaluation of chromosome instability can be performed by using, as an indicator, variation in interaction or bonding between HP1 and INCENP. This evaluation system can be used for screening for an anticancer agent based on a new concept that the chromosome instability of a cancer cell can be targeted.SELECTED DRAWING: None