RNA aptamer, complex molecule, pH determination method, labeled RNA and method for producing labeled RNA

摘要

PROBLEM TO BE SOLVED: To enhance the luminescence of a luminescent probe when interacting with the luminescent probe, as compared with the case where the RNA aptamer is an RNA aptamer having only the base sequence of a luminescence-induced aptamer capable of interacting with the luminescent probe. To provide RNA aptamers. SOLUTION: The triple chain includes a base sequence of a luminescence-inducing aptamer that interacts with a luminescence probe to induce luminescence, and a triple-strand-forming base sequence group capable of forming a triple chain in a cooperative manner. The forming base sequence group consists of a first base sequence consisting of 8 or more consecutive urides bound to one end of the luminescence-inducing aptamer and 8 or more consecutive adenosine bound to the other end. It has a second base sequence consisting of and a third base sequence consisting of 8 or more consecutive uridines, and the first base sequence, the second base sequence and the third base sequence It is an RNA aptamer capable of forming triple strands cooperatively. [Selection diagram] None