首页> 外国专利> NUCLEIC ACID SENSOR FOR ANALYZING ORAL CAVITY BACTERIA, ANALYSIS DEVICE OF ORAL CAVITY BACTERIA, AND ANALYSIS METHOD OF ORAL CAVITY BACTERIA

NUCLEIC ACID SENSOR FOR ANALYZING ORAL CAVITY BACTERIA, ANALYSIS DEVICE OF ORAL CAVITY BACTERIA, AND ANALYSIS METHOD OF ORAL CAVITY BACTERIA

机译:核酸传感器用于口腔细菌的分析,口腔细菌的分析装置以及口腔细菌的分析方法

摘要

To provide a sensor which can be used for analyzing an oral cavity flora and can specifically and easily detect oral cavity bacteria.SOLUTION: A nucleic acid sensor comprises a nucleic acid molecule in which a block sequence Bof a nucleic acid sequence C and a nucleic acid sequence D and a block sequence Bof the nucleic acid sequence D and the nucleic acid sequence C are coupled in this order. The nucleic acid sequence C is a nucleic acid sequence which anneals to a target nucleic acid in a sequence dependent manner, the block sequence Bis a nucleic acid sequence which anneals to a partial region of the nucleic acid sequence C in a sequence dependent manner, the nucleic acid sequence D is a nucleic acid sequence which causes a catalytic function, and the block sequence Bis a nucleic acid sequence which anneals to a partial region of the nucleic acid sequence D in a sequence dependent manner. Under existence of the target nucleic acid, the target nucleic acid couples to the nucleic acid sequence C in the nucleic acid molecule, the nucleic acid sequence C and the block sequence Bare separated, and the nucleic acid sequence D and the block sequence Bare separated, and thereby a catalytic function of the nucleic acid sequence D becomes in an on state.SELECTED DRAWING: Figure 1
机译:为了提供一种可用于分析口腔菌群并能够特异性且容易地检测口腔细菌的传感器。解决方案:核酸传感器包括核酸分子,其中核酸序列C的嵌段序列B和核酸核酸序列D和核酸序列C的序列D和嵌段序列B以该顺序偶联。核酸序列C是以序列依赖性方式与靶核酸退火的核酸序列,嵌段序列Bis是以序列依赖性方式与核酸序列C的部分区域退火的核酸序列。核酸序列D是引起催化功能的核酸序列,嵌段序列Bis是以依赖序列的方式与核酸序列D的部分区域退火的核酸序列。在存在靶核酸的情况下,靶核酸与核酸分子中的核酸序列C偶联,核酸序列C和嵌段序列Bare分离,核酸序列D和嵌段序列Bare分离,从而使核酸序列D的催化功能处于开启状态。

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