QUINOLINE DERIVATIVES AS TAM RTK INHIBITORS

摘要

PROBLEM TO BE SOLVED: To provide quinoline derivatives as TAM RTK inhibitors.;SOLUTION: The present invention relates to novel compounds which are inhibitors of TAM (Axl, Mer and Tyro 3) and/or Met family receptor tyrosine kinases (RTK's). These compounds are suitable for the treatment of disorders associated with, accompanied by, caused by or induced by a receptor of the TAM family, in particular a hyperfunction thereof. The compounds are suitable for the treatment of hyperproliferative disorders, such as cancer, particularly immune-suppressive cancer, refractory cancer and cancer metastases.;SELECTED DRAWING: None;COPYRIGHT: (C)2020,JPO&INPIT