Provided are immunogenic compositions containing antigens that are porcine circovirus type 3 and porcine circovirus type 2. The immunogenic composition comprises an immunizing amount of the porcine circovirus type 3 antigen, an immunizing amount of the porcine circovirus type 2 new gene subtype antigen, and a pharmaceutically acceptable carrier. The immunogenic composition has good immunogenicity and can completely protect against a mixed infection of porcine circovirus type 3 and porcine circovirus type 2 with a single immunization.
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