Ibandronate conjugates of nucleoside antimetabolites

摘要

Nucleoside metabolite antagonists and conjugates of their analogs and ibandronates, pharmaceutical compositions containing one or more of the conjugates, methods for synthesizing the conjugates, and conjugates. Methods for treating diseases and / or conditions using are provided herein. Nucleoside antimetabolites and their analogs can be selected from the group consisting of cytarabine, gemcitabine, clofarabine, cladribine, vidaza, dacogen, fludarabine, floxuridine, nelarabine and pentostatin.