首页> 外国专利> NOVEL IMMUNOTHERAPY FOR SEVERAL TUMORS OF BLOOD, IN PARTICULAR CHRONIC LYMPHATIC LEUKEMIA (CLL)

NOVEL IMMUNOTHERAPY FOR SEVERAL TUMORS OF BLOOD, IN PARTICULAR CHRONIC LYMPHATIC LEUKEMIA (CLL)

机译:新型血液疗法治疗多种血液,尤其是慢性淋巴细胞白血病(CLL)

摘要

To provide peptides for use in immunotherapy.SOLUTION: The invention relates to peptides, nucleic acids and cells. In particular, the invention relates to cancer immunotherapy. The invention further relates to a tumor-associated cytotoxic T cell (CTL) peptide epitope that serves as an active pharmaceutical ingredient of a vaccine combination that stimulates anti-tumor immune response singly or in combination with another tumor associated peptides. The invention relates to several peptide sequences derived from human tumor cell HLA class I and HLA class II molecules and variants thereof usable in a vaccine composition for eliciting anti-tumor immune response.SELECTED DRAWING: None
机译:提供用于免疫疗法的肽。解决方案:本发明涉及肽,核酸和细胞。特别地,本发明涉及癌症免疫疗法。本发明进一步涉及肿瘤相关的细胞毒性T细胞(CTL)肽表位,其充当疫苗组合的活性药物成分,所述疫苗组合单独或与另一种肿瘤相关的肽组合刺激抗肿瘤免疫应答。本发明涉及衍生自人肿瘤细胞I类HLA和II类HLA分子的几种肽序列及其变体,可用于疫苗组合物中以引发抗肿瘤免疫反应。

著录项

  • 公开/公告号JP2020014460A

    专利类型

  • 公开/公告日2020-01-30

    原文格式PDF

  • 申请/专利权人 IMMATICS BIOTECHNOLOGIES GMBH;

    申请/专利号JP20190132609

  • 申请日2019-07-18

  • 分类号C12N15/12;C07K7/06;C07K7/08;C07K14/47;C07K14/725;C07K19;C07K14/74;C12N15/62;C12N15/63;C12N5/10;C12N5/0784;C12P21/02;C12N5/0783;C12Q1/6809;C12Q1/02;C12Q1/6869;A61K38/08;A61K38/10;A61K38/16;A61K39;A61P35;A61P35/02;A61K35/12;A61K35/17;A61K38/17;A61K35/76;A61K48;G01N33/50;G01N33/15;G01N33/53;G01N37;

  • 国家 JP

  • 入库时间 2022-08-21 11:36:00

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