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METHOD AND APPARATUS FOR PROVIDING PHARMACOKINETIC DRUG DOSING REGIMEN

机译:提供药动学给药方案的方法和装置

摘要

To provide a method for providing a therapeutic plasma protein dosing regimen.SOLUTION: A method comprises the steps of: determining an estimated pharmacokinetic profile of a patient based upon at least one of a body weight and an age of a patient; determining a first dosing regime for a first specified dosing interval including (i) a first dosage and (ii) a first therapeutic plasma protein level in the patient changing over time on the basis at least of an estimated pharmacokinetic profile; determining a second dosing regimen for a second specified dosing interval including (i) a second dosage and (ii) a second therapeutic plasma protein level in the patient changing over time on the basis at least of the estimated pharmacokinetic profile; and displaying the first dosing regimen and the second dosing regimen on a client device such that the first dosing regimen is displayed in conjunction with the second dosing regimen.SELECTED DRAWING: Figure 1
机译:提供一种提供治疗性血浆蛋白给药方案的方法。解决方案:一种方法包括以下步骤:基于患者的体重和年龄中的至少一个来确定患者的估计药代动力学特征;至少基于估计的药代动力学曲线,确定针对第一指定给药间隔的第一给药方案,所述第一指定给药间隔包括(i)第一剂量和(ii)患者中随时间变化的第一治疗血浆蛋白水平;在第二指定的给药间隔中确定第二给药方案,所述第二指定给药间隔包括至少基于所述估计的药代动力学特征,所述患者中的(i)第二剂量和(ii)第二治疗血浆蛋白水平随时间变化;在客户端设备上显示第一给药方案和第二给药方案,以使第一给药方案与第二给药方案结合显示。

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