首页> 外国专利> A PLK1-derived antigenic determinant specific for the HLA-A2 subtype that induces an immune response of T cells specific for the PLK1 protein antigen.

A PLK1-derived antigenic determinant specific for the HLA-A2 subtype that induces an immune response of T cells specific for the PLK1 protein antigen.

机译:对HLA-A2亚型具有特异性的PLK1衍生抗原决定簇,可诱导对PLK1蛋白抗原具有特异性的T细胞的免疫应答。

摘要

TECHNICAL FIELD The present invention relates to an HLA-A2 subtype-specific PLK1-derived antigenic determinant that induces an antigen-specific T cell immune response against PLK1 protein. More specifically, the present invention relates to an antigen-specific PLK1 protein-specific antigenic determinant. A PLK1-derived antigenic determinant specific for the HLA-A2 subtype that induces a specific T cell immune response can provide a CD8+ T cell immune response specific for tumor cells.
机译:HLA-A2亚型特异性PLK1衍生抗原决定簇技术领域本发明涉及HLA-A2亚型特异性PLK1衍生抗原决定簇,其诱导针对PLK1蛋白的抗原特异性T细胞免疫应答。更具体地,本发明涉及抗原特异性PLK1蛋白特异性抗原决定簇。对HLA-A2亚型具有特异性的PLK1衍生抗原决定簇可以诱导特定的T细胞免疫应答,从而可以提供对肿瘤细胞具有特异性的CD8 + T细胞免疫应答。

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