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External preparation for treatment of onychomycosis

机译:外用制剂治疗灰指甲

摘要

The present invention relates to a non-coating external treatment for onychomycosis comprising a medium-chain fatty acid triglyceride as a non-volatile component. provide. In particular, the present invention provides an external treatment for onychomycosis comprising an antifungal active substance such as efinaconazole, a volatile component, an additive such as a medium chain fatty acid triglyceride, and a permeation enhancer such as ethyl lactate. This preparation has significantly improved nail permeability, and has excellent properties as a pharmaceutical from the viewpoint of medicinal properties and physical properties of the preparation.
机译:本发明涉及一种用于甲癣的非包衣外用治疗剂,其包含中链脂肪酸甘油三酸酯作为非挥发性组分。提供。特别地,本发明提供了一种用于甲癣的外用治疗剂,其包含抗真菌活性物质例如艾芬那康唑,挥发性成分,添加剂例如中链脂肪酸甘油三酸酯和渗透促进剂例如乳酸乙酯。从制剂的医学性质和物理性质的观点来看,该制剂具有显着改善的指甲渗透性,并且具有优异的药物性质。

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