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CROSS-VALIDATION BASED CALIBRATION OF SPECTROSCOPIC MODEL
CROSS-VALIDATION BASED CALIBRATION OF SPECTROSCOPIC MODEL
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机译:基于交叉验证的光谱模型校正
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摘要
To provide a spectroscopy based method for quality control of pharmaceutical products allowing determination of whether component ingredients of a medical material of a pharmaceutical product correspond to a packaging label associated with the medical material.SOLUTION: A device may receive a master data set 160 for a first spectroscopic model; receive a target data set for a target population 164 associated with the first spectroscopic model to update the first spectroscopic model; generate a training data set that includes the master data set and first data from the target data set; generate a validation data set that includes second data from the target data set and does not include the master data set; generate, using cross-validation and using the training data set and the validation data set, a second spectroscopic model that is an update of the first spectroscopic model; and provide the second spectroscopic model.SELECTED DRAWING: Figure 1B
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