THERAPEUTIC DOSING OF NEUREGULIN OR SUBSEQUENCE THEREOF FOR TREATMENT OR PROPHYLAXIS OF HEART FAILURE

摘要

PROBLEM TO BE SOLVED: To provide treatment of heart failure in a mammal, and specifically, a dosing regimen for maintaining and/or enhancing therapeutic benefits while concomitantly minimizing any potential side effects.;SOLUTION: A method comprises: administering a therapeutically effective amount of a peptide comprising an epidermal growth factor-like (EGF-like) domain to a mammal at intervals of at least 48 hours. In an administration method, the peptide is recombinant human glial growth factor 2 (GGF2).;SELECTED DRAWING: None;COPYRIGHT: (C)2020,JPO&INPIT