Next-generation sequencing-based method for simultaneous detection of microsatellite loci stability and genomic changes

摘要

The present invention relates to a method for simultaneously detecting the stability and genomic alteration of microsatellite loci based on next generation sequencing (prettyMSI), in particular the use of said detection method in the auxiliary diagnosis of colorectal cancer patients, and a corresponding kit. provide. Said microsatellite loci are selected from the 22 microsatellite loci as shown in Table 1 or any combination of 15, 16, 17, 18, 19, 20, 21 loci therein. .