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Sequence conversion and signal amplification DNA having a poly DNA spacer sequence and detection methods using them
Sequence conversion and signal amplification DNA having a poly DNA spacer sequence and detection methods using them
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机译:具有多DNA间隔子序列的序列转换和信号放大DNA及其检测方法
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摘要
Disclosed are methods for detecting a target nucleic acid in a sample. The methods include contacting said sample, in the presence of a polymerase and an endonuclease, with a sequence conversion oligonucleotide. Also disclosed are methods for detecting a target nucleic acid in a sample in which said sample is contacted, in the presence of a polymerase and an endonuclease, with a sequence conversion oligonucleotide and a signal amplifier oligonucleotide. The disclosure also provides compositions and kits comprising such sequence conversion and signal amplifier oligonucleotides.
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