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Pharmaceutical compositions containing glutarimide derivatives, and their application for treating eosinophilic diseases

机译:含有戊二酰亚胺衍生物的药物组合物及其在治疗嗜酸性粒细胞疾病中的应用

摘要

The present invention relates to novel biologically active glutarimide derivatives of general formula (I) or a pharmaceutically acceptable salt thereof, their use as a therapeutic agent for the treatment of eosinophilic diseases, preferably of allergic nature, in particular bronchial asthma, allergic rhinitis, polypous rhinosinusopathies, eosinophilic colitis, eosinophilic syndrome, allergic conjunctivitis, atopic dermatitis, Churg-Strauss syndrome, anaphylactic shock, Quincke's edema, eosinophilic vasculitis, eosinophylic esophagitis, eosinophilic gastroenteritis, or fibroses. The invention also relates to pharmaceutical compositions comprising glutarimide derivatives of general formula (I):
机译:本发明涉及通式(I)的新型生物活性戊二酰亚胺衍生物或其药学上可接受的盐,它们用作治疗嗜酸性粒细胞疾病的治疗剂的用途,所述嗜酸性粒细胞疾病优选是过敏性的,特别是支气管哮喘,过敏性鼻炎,息肉鼻-鼻窦病,嗜酸性结肠炎,嗜酸性综合症,过敏性结膜炎,特应性皮炎,Churg-Strauss综合征,过敏性休克,Quincke水肿,嗜酸性血管炎,嗜酸性食管炎,嗜酸性肠胃炎或嗜酸性肠炎。本发明还涉及包含通式(I)的戊二酰亚胺衍生物的药物组合物:

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