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Pharmaceutical composition comprising glutarimide derivatives, and application thereof for treating eosinophilic diseases

机译:包含戊二酰亚胺衍生物的药物组合物及其在治疗嗜酸性粒细胞疾病中的应用

摘要

#$%^&*AU2018264084C120200827.pdf#####ABSTRACT The present invention relates to novel biologically active glutarimide derivatives of general formula (I) or a pharmaceutically acceptable salt thereof, their use as a therapeutic agent for the treatment of eosinophilic diseases, preferably of allergic nature, in particular bronchial asthma, allergic rhinitis, polypous rhinosinusopathies, eosinophilic colitis, eosinophilic syndrome, allergic conjunctivitis, atopic dermatitis, Churg-Strauss syndrome, anaphylactic shock, Quincke's edema, eosinophilic vasculitis, eosinophylic esophagitis, eosinophilic gastroenteritis, or fibroses. The invention also relates to pharmaceutical compositions comprising glutarimide derivatives of general formula (T): R1 N 0
机译:#$%^&* AU2018264084C120200827.pdf #####抽象本发明涉及新型生物活性物质通式(I)的戊二酰亚胺衍生物或其药学上可接受的盐,其作为药物的用途治疗嗜酸性粒细胞疾病的治疗剂,优选具有过敏性质,特别是支气管哮喘,过敏性鼻炎,鼻窦息肉病,嗜酸性结肠炎,嗜酸性综合征,过敏性结膜炎,特应性皮炎,Churg-Strauss综合征,过敏性休克,昆克氏水肿,嗜酸性血管炎,嗜酸性食管炎,嗜酸性肠胃炎或纤维化。本发明也涉及包含戊二酰亚胺的药物组合物通式(T)的导数:R1ñ0

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