A diagnostic method for prostate disease through bacterial metagenomic analysis

摘要

The present invention relates to a method for diagnosing prostate diseases such as prostate cancer and benign prostatic hyperplasia through bacterial metagenomic analysis, and more specifically, performing bacterial metagenomic analysis using a sample derived from a subject, and The present invention relates to a method for diagnosing prostate cancer and benign prostatic hyperplasia by analyzing changes in vesicle content. Extracellular vesicles secreted by the bacteria present in the environment are absorbed into the body and can have a direct effect on inflammation and the development of cancer. At present, it is difficult to perform an efficient treatment because it is difficult to make an early diagnosis before appearing. By predicting the risk of developing benign prostatic hyperplasia in advance, it is possible to diagnose and predict at-risk groups of prostate disease at an early stage and delay the onset or prevent onset of disease by appropriate management. Since the diagnosis can be made early even after the onset of cancer, the incidence of prostate disease can be reduced and the therapeutic effect can be increased. [Selection diagram] FIG.