首页>
外国专利>
Method for preparing 4-aminoindane derivative and related aminoindane amide
Method for preparing 4-aminoindane derivative and related aminoindane amide
展开▼
机译:4-氨基茚满衍生物及相关氨基茚满酰胺的制备方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
A process for preparation of 4-aminoindane compounds of a first formula, salts and enantiomers thereof including: a) hydrogenating a 1,2-dihydroquinoline of a second formula to give a corresponding tetrahydroquinoline of a third formula; b) acylating the tetrahydroquinoline of the third formula with a carboxylic acid derivative of a fourth formula to obtain a corresponding acyl derivative compound of a fifth formula; c) rearranging the acyl derivative compound of the fifth formula under acidic conditions so as to give an acyl indane compound of a sixth formula or an addition salt thereof; and d) hydrolysing the acyl group of the acyl indane compound of the sixth formula so as to obtain the 4-aminoindane derivatives of the first formula.
展开▼