A novel compound having therapeutic activity against Mycobacterium avium complex infection and its production method

摘要

The present invention is a novel compound having antibacterial activity against Mycobacterium avium and Mycobacterium avium intracellulare, which are the causative bacteria of MAC disease, and having a skeletal structure different from that of known therapeutic agents for MAC disease. The challenge is to provide. One aspect of the present invention is in formula (I) [wherein R1 is synonymous with the definition described in the specification or claims. ], Or a salt thereof, or a solvate thereof. Another aspect of the present invention is a method for producing a compound represented by the formula (I) or a salt thereof, or a solvate thereof, and a compound or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof. It also relates to a therapeutic agent for Mycobacterium avium complex infection (MAC disease) containing the solvate to be used as an active ingredient.