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NUCLEOTIDE SEQUENCES HYBRIDIZING SPECIFICALLY WITH THE MYCOBACTERIUM AVIUM-INTRACELLULARE COMPLEX BACTERIAL STRAINS, THEIR USE AS OLIGONUCLEOTIDE PRIMERS AND NUCLEOTIDE PROBES; METHOD FOR THE IDENTIFICATION OF THE MYCOBACTERIUM AVIUM-INTRACELLULARE COMPLEX MYCOBACTERIA NECESSARY FOR THE...
NUCLEOTIDE SEQUENCES HYBRIDIZING SPECIFICALLY WITH THE MYCOBACTERIUM AVIUM-INTRACELLULARE COMPLEX BACTERIAL STRAINS, THEIR USE AS OLIGONUCLEOTIDE PRIMERS AND NUCLEOTIDE PROBES; METHOD FOR THE IDENTIFICATION OF THE MYCOBACTERIUM AVIUM-INTRACELLULARE COMPLEX MYCOBACTERIA NECESSARY FOR THE...
the present invention 2122367 9309251 pctabs00162 is a nucleic acid sequence which specifically hybrid with a genomic nucleic acid sequence of strains belonging to the fullmycobacterium avium intracellulare, chosen from the nucleotide sequence seq id nu00b71, the nucleotide sequence seq id nu00b72, complementary sequences thereof.and the sequences which differ by mutation, insertion, deletion or substitution of one or more bases.and that hybrid with nucleic acids of mycobacteria not belonging to that complex.fragments of this sequence can be used as specific primers for the amplification of specific sequences of strains belonging to the complex.avium intracellulare specific nucleic probes and nucleic sequences of strains belonging to the complex, m. avium intracellulare.the invention also relates to a method for detecting the presence of strains belonging to the complex.avium intracellulare in a biological sample, as well as a prerequisite for the implementation of the method.
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机译:本发明2122367 9309251 pctabs00162是一种核酸序列,该核酸序列与属于鸟内满分枝杆菌细胞内菌株的基因组核酸序列特异性杂交,所述菌株选自核苷酸序列seq id n u00b71,核苷酸序列seq id n u00b72,互补其序列,以及因一个或多个碱基的突变,插入,缺失或取代而不同的序列,以及与不属于该复合物的分枝杆菌核酸杂交的序列。该序列的片段可用作扩增DNA的特异性引物。属于该复合物的菌株的特定序列。鸟细胞内特异性核酸探针和属于该复合物的菌株的核酸序列,m。本发明还涉及一种用于检测生物样品中属于细胞内禽复合体的菌株的存在的方法,以及实施该方法的前提。
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