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Method for producing hetero-type monodisperse polyethylene glycol and intermediate for producing hetero-type monodisperse polyethylene glycol
Method for producing hetero-type monodisperse polyethylene glycol and intermediate for producing hetero-type monodisperse polyethylene glycol
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机译:杂型单分散聚乙二醇的制备方法及杂型单分散聚乙二醇的中间体
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摘要
Provided is a hetero type monodispersed polyethylene glycol which contains a compound represented by formula (1) ((1): NH 2 -(CH 2 CH 2 O) a -CH 2 CH 2 COOH (in formula (1), a is an integer between 6 and 40)) and in which the following each satisfy a specified relational expression: (A) a chromatogram detected by a differential refractometer when separation is carried out using reversed phase chromatography; (B) a chromatogram detected by a differential refractometer when separation is carried out using cation exchange chromatography; and (C) a chromatogram detected by a differential refractometer when the hetero type monodispersed polyethylene glycol containing a compound represented by formula (1) is derivatized and separation is carried out using anion exchange chromatography.
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