首页> 外国专利> AQUAPORIN EXPRESSION ENHANCER CONTAINING SASA VEITCHII EXTRACT PREPARATION AS ACTIVE INGREDIENT AND HEALING PROMOTER CONTAINING THE SAME AS WELL AS PRODUCTION METHOD THEREOF

AQUAPORIN EXPRESSION ENHANCER CONTAINING SASA VEITCHII EXTRACT PREPARATION AS ACTIVE INGREDIENT AND HEALING PROMOTER CONTAINING THE SAME AS WELL AS PRODUCTION METHOD THEREOF

机译:包含SASA VEITCHII提取物制剂的AQUAPORIN表达增强剂,作为活性成分,并且包含相同成分的治疗促进剂及其生产方法

摘要

To provide agents for use in healing agent compositions containing as an active ingredient Sasa veitchii extract in which variation in medicinal effects due to factors such as production area, collection year, extract extraction method, and the like is reduced and effective quality is guaranteed.SOLUTION: We found that a purified concentrated extract with low polarity obtained by separating and fractioning by reverse-phase chromatography the purified and concentrated extract fractionated from Sasa veitchii hot water extraction fraction into water-immiscible solvent has an aquaporin expression-enhancing activity and a hair papilla cell proliferation-enhancing activity. This provides an active ingredient of a medicament or food having a healing promoting effect based on the aquaporin expression enhancer and hair papilla cell proliferation enhancement.SELECTED DRAWING: Figure 1
机译:本发明提供用于含有沙棘提取物作为有效成分的愈合剂组合物中的药剂,该药剂可减少由于生产面积,采集年限,提取物提取方法等因素引起的药效变化并保证有效质量。 :我们发现,通过反相色谱分离和分级分离从Sasa veitchii热水提取馏分中分离到水不混溶溶剂中的纯化和浓缩提取物获得的低极性纯化浓缩提取物具有水通道蛋白表达增强活性和毛乳头。细胞增殖增强活性。这提供了基于水通道蛋白表达增强剂和毛发乳头细胞增殖增强作用而具有促进愈合作用的药物或食品的活性成分。图1:

著录项

  • 公开/公告号JP2020002054A

    专利类型

  • 公开/公告日2020-01-09

    原文格式PDF

  • 申请/专利权人 HOSHI SEIYAKU KK;

    申请/专利号JP20180122677

  • 申请日2018-06-28

  • 分类号A61K36/899;A61P43;A61P17;A61P17/14;A61P1/04;A61P13/12;A61P1/16;A23L33/105;

  • 国家 JP

  • 入库时间 2022-08-21 11:31:55

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