HIGH DOSAGE STRENGTH TABLETS OF RUCAPARIB

摘要

PROBLEM TO BE SOLVED: To provide a tablet including high dosage of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one camsylate.;SOLUTION: The invention is directed to high dosage strength tablets of rucaparib. In some embodiments, the tablet includes 45-90% w/w rucaparib camsylate. In some embodiments, the dry granulated tablet includes 45-90% w/w rucaparib camsylate. One such embodiment is a tablet containing at least 200 mg rucaparib. Another embodiment is a tablet containing at least 300 mg rucaparib.;SELECTED DRAWING: Figure 1;COPYRIGHT: (C)2020,JPO&INPIT