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Cell structure and method for producing cell structure

机译:泡孔结构和产生泡孔结构的方法

摘要

An object of the present invention is to provide a cell structure which does not contain glutaraldehyde and can form blood vessels after transplantation, and a method for producing the above-described cell structure. According to the present invention, there is provided a cell structure which contains a biocompatible macromolecular block and at least one kind of cell and has voids and in which a plurality of the biocompatible macromolecular blocks are arranged in gaps between a plurality of the cells, in which a ratio of the volume of the biocompatible macromolecular blocks with respect to the volume of the cell structure is 10% to 30%, a ratio of the volume of the cells with respect to the volume of the cell structure is 20% to 50%, and a ratio of the volume of the voids with respect to the volume of the cell structure is 35% to 60%.
机译:本发明的目的是提供一种不包含戊二醛且在移植后可以形成血管的细胞结构,以及用于制造上述细胞结构的方法。根据本发明,提供了一种细胞结构,其包含生物相容性大分子嵌段和至少一种细胞并且具有空隙,并且其中多个生物相容性大分子嵌段排列在多个细胞之间的间隙中。其中生物相容性大分子嵌段的体积相对于细胞结构的体积的比例为10%至30%,细胞的体积相对于细胞结构的体积的比例为20%至50%并且,空隙的体积相对于单元结构的体积的比例为35%〜60%。

著录项

  • 公开/公告号US10471180B2

    专利类型

  • 公开/公告日2019-11-12

    原文格式PDF

  • 申请/专利权人 FUJIFILM CORPORATION;

    申请/专利号US201615374604

  • 发明设计人 REIKO IWAZAWA;KENTARO NAKAMURA;

    申请日2016-12-09

  • 分类号A61L27/38;A61L27/22;A61K35/28;A61L27;C07K14/78;A61L27/50;A61L27/56;

  • 国家 US

  • 入库时间 2022-08-21 11:30:25

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