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Use of landiolol hydrochloride in the long-term treatment of tachyarrhythmias

机译:盐酸landiolol在长期治疗快速性心律失常中的用途

摘要

The invention provides a new use of landiolol hydrochloride for persistent reduction of the heart rate during the administration period of landiolol hydrochloride in the treatment of a human suffering from tachycardia, tachyarrhythmia or elevated blood pressure, wherein landiolol hydrochloride is administered at a constant dose of more than 5 μg/kg/min, specifically of at least 10 μg/kg/min for a period of at least 2 hours and wherein the heart rate and/or blood pressure of said patient are persistently reduced during the administration period compared to the heart rate and/or blood pressure before treatment and no overshooting effect occurs after termination of said administration.
机译:本发明提供了盐酸兰地洛尔在盐酸兰地洛尔的给药期间在治疗心动过速,快速性心律失常或血压升高的人中持续降低心率的新用途,其中盐酸兰地洛尔以恒定剂量或更高的剂量给药。小于5μg/ kg / min,特别是至少10μg/ kg / min,持续至少2小时,并且其中所述患者的心率和/或血压在施用期间与心脏相比持续降低终止治疗前的速率和/或血压,并且在终止所述给药后没有过调作用。

著录项

  • 公开/公告号US10722516B2

    专利类型

  • 公开/公告日2020-07-28

    原文格式PDF

  • 申请/专利权人 AOP ORPHAN PHARMACEUTICALS AG;

    申请/专利号US201414787217

  • 发明设计人 GÜNTHER KRUMPL;

    申请日2014-04-25

  • 分类号A61K31/5377;A61K9/08;

  • 国家 US

  • 入库时间 2022-08-21 11:29:21

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