Compounds and methods for the synthesis of 5-(N-protected-tryptaminocarboxyamide)-2′-deoxyuridine phosphoramidite for incorporation into a nucleic acid

摘要

Modified Tryptamine, Tryptamine-2′-deoxy-uridine (TrpdU) and TrpdU-phosphoramidites for oligonucleotide synthesis are provided, as well as improved methods of their synthesis and oligonucleotides comprising at least one modified TrpdU nucleotide.