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Pneumococcal serotypes

机译：肺炎球菌血清型

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摘要

Disclosed is a new and emerging serotype of Streptococcus pneumoniae designated serotype 6C, and assays and monoclonal antibodies useful in identifying same. Also disclosed is a novel pneumococcal polysaccharide with the repeating unit {→2) glucose 1 (1→3) glucose 2 (1→3) rhamnose (1→3) ribitol (5→phosphate}. This new serotype may be included in pneumococcal vaccines.

机译：公开了肺炎链球菌指定的血清型6C的新型血清型，以及可用于鉴定的血清型和单克隆抗体。还公开了一种新型的肺炎球菌多糖，其具有重复单元{→2）葡萄糖1（1→3）葡萄糖2（1→3）鼠李糖（1→3）核糖醇（5→磷酸酯）。这种新的血清型可包括在肺炎球菌中疫苗。 展开▼

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公开/公告号US10634685B2

专利类型

公开/公告日2020-04-28

原文格式PDF

申请/专利权人 THE UAB RESEARCH FOUNDATION;FUNDACAO OSWALDO CRUZ;INSTITUTO ADOLFO LUTZ;
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申请/专利号US201715723136

发明设计人 MOON H. NAHM;JISHENG LIN;ANGELA P. BRANDAO;MARIA CRISTINA BRANDILEONE;
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申请日2017-10-02

分类号G01N33/68;A61K31/715;A61K39/09;C07K16/12;C08B37;C12Q1/14;C12R1/46;G01N33/569;

国家 US

入库时间 2022-08-21 11:28:31

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3. Pneumococcal polysaccharide serotype 1,4,5,6B, 7F, 9V, 14 and 23F conjugated to D proteins (derived from non-typeable Haemophilus influenzae); 18C polysaccharide pneumococcal serotype conjugated to transporter tetanus toxoid protein; 19F Polysaccharide Pneumococcal Serotype Conjugated to Transporter Diphtheria Toxoid Protein (SYNFLORIX - Conjugated Polysaccharide Pneumococcal Vaccine (Adsorbed) [P] . LU91609I2 . 2009-11-24

机译：与D蛋白结合的肺炎球菌多糖血清型1、4、5、6B，7F，9V，14和23F（来源于不可分型的流感嗜血杆菌）;与转运破伤风类毒素蛋白缀合的18C多糖肺炎球菌血清型;与转运白喉类毒素蛋白结合的19F多糖肺炎球菌血清型（SYNFLORIX-结合多糖肺炎球菌疫苗（吸附）

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机译：具有肺炎球菌血清型的多糖的生产方法。

5. PRODUCTION METHOD FOR CAPSULAR POLYSACCHARIDE HAVING PNEUMOCOCCAL SEROTYPE [P] . CA2884241C . 2018-11-20

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