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Genetic engineering of non-human animals for the production of chimeric antibodies
Genetic engineering of non-human animals for the production of chimeric antibodies
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机译:非人类动物的基因工程以生产嵌合抗体
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摘要
The invention provides non-human cells and mammals having a genome encoding chimeric antibodies and methods of producing transgenic cells and mammals. Certain aspects of the invention include chimeric antibodies, humanized antibodies, pharmaceutical compositions and kits. Certain aspects of the invention also relate to diagnostic and treatment methods using the antibodies of the invention.
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